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Managing Developmental Delays and Disabilities

A Spotlight on the Scientific Statement

Better and earlier identification of cardiac neurodevelopmental delays and disabilities benefits patients through access to appropriate treatments and interventions. This article describes best practices in managing neurodevelopmental delays or disabilities in patients with CHDs, as described by Sood et al (2024).

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Family Education

Clinicians should teach families about their children's developmental profile, and their ongoing risk of neurodevelopmental delay and disability. This means:

  • information about any identified delays or disorders

    • description

    • expected outcomes

    • recommended interventions

    • relevant resources

  • referral for additional medical evaluation(s) as needed, with a clear explanation for why the further testing is warranted

  • information about any worrisome symptoms or behaviors, and how they should be monitored

  • a clear plan for further developmental surveillance or evaluation, according to risk category, and an explanation for this recommendation

Management in Infants and Toddlers

Early and appropriate intervention gives children the best chance of a positive outcome. The following practices are recommended for infants and toddlers:

  • referral to Early Intervention (EI) for children ages 0-35 months

  • enrollment in preschool

    • public preschool through Special Education for children ages 3-5 with disabilities that affect their ability to make progress in the curriculum

    • Head Start for children who meet requirements or who are filling disability quota

    • private preschool, public preschool in states with universal access, or public preschool for children without disabilities enrolling as peer models

  • clinic-based services

    • occupational therapy (OT)

    • physical therapy (PT)

    • speech and language therapy

    • developmental behavioral pediatric care

  • family-based interventions

Management in School-Age Children and Adolescents

These strategies have been identified as best practices for the management of neurodevelopmental delays and disabilities in school-age children and adolescents with CHDs:

  • Special Education services through an individualized education plan (IEP), for students with disabilities that limit their capacity to make progress in the curriculum

  • 504 Plans for students whose disabilities reduce their access to the curriculum, but who can make typical progress when they have equal access

  • neurodevelopmental evaluation to assist in accessing appropriate school services

  • exercise training

  • pharmacological treatment of psychiatric disorders

Management in Young Adults

Appropriate management of neurodevelopmental disabilities in adulthood may include:

  • transition assessment, planning, and services

  • clinic-based services

    • psychoeducational programs to promote health-related quality of life

    • reviewing medications in consideration of effects on neuropsychological functioning

    • counseling on tobacco use

    • counseling on aerobic exercise

    • early collaboration of cardiologists and neurologists specializing in coagulopathies and stroke for patients with hematologic or neurological comorbidities

  • therapy with a psychologist

  • pharmaceutical treatment of psychiatric disorders

  • job training and vocational programs

These links are provided as resources only. Boston Children's Hospital and the Benderson Family Heart Center don't necessarily endorse all of the information on these sites.

Long-Term Quality of Life

Patients with CHDs are at risk of neurodevelopmental comorbidities through the lifespan, which can substantially reduce quality of life if not properly managed. Through proactive planning and well-timed interventions, professionals can help patients to optimize their functioning and personal fulfillment through the course of development and into adulthood.

This content was reviewed by staff at Boston Children's Hospital's Cardiac Neurodevelopmental Program.

Bassok, D., Gibbs, C. R., & Latham, S. (2019). Preschool and children's outcomes in elementary school: Have patterns changed nationwide between 1998 and 2010?. Child Development, 90(6), 1875-1897.https://files.eric.ed.gov/fulltext/ED586377.pdf
Cohen, S., & Earing, M. G. (2018). Neurocognitive impairment and its long-term impact on adults with congenital heart disease. Progress in cardiovascular diseases, 61(3-4), 287-293.https://www.sciencedirect.com/science/article/abs/pii/S0033062018301658
Ferguson, M., & Kovacs, A. H. (2016). An integrated adult congenital heart disease psychology service. Congenital heart disease, 11(5), 444-451.https://onlinelibrary.wiley.com/doi/pdf/10.1111/chd.12331?casa_token=tYoGCL6Q0FEAAAAA%3ADx55GbdRL1P1566dWC1qfpv1gnNH0idVF7cN_y_FABocGkv1E8MA4mLgnZfgMCORj-2e22dZTiNf9g
Frolek Clark, G. J., & Schlabach, T. L. (2013). Systematic review of occupational therapy interventions to improve cognitive development in children ages birth–5 years. The American Journal of Occupational Therapy, 67(4), 425-430.https://research.aota.org/ajot/article-abstract/67/4/425/1162/Systematic-Review-of-Occupational-Therapy
Gaynor, J. W., Stopp, C., Wypij, D., Andropoulos, D. B., Atallah, J., Atz, A. M., ... & International Cardiac Collaborative on Neurodevelopment (ICCON) Investigators. (2015). Neurodevelopmental outcomes after cardiac surgery in infancy. Pediatrics, 135(5), 816-825.https://watermark.silverchair.com/peds_2014-3825.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAA6QwggOgBgkqhkiG9w0BBwagggORMIIDjQIBADCCA4YGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMqtW31I8tNewE_9ThAgEQgIIDV6VjQMaBA-NDdM5Nh24xLKtFQ1DK7L7_F6XWNo5esFI4PbnKA4-l-cioDUHzcs8E0sTm9pRVSRS5sJVpHPDC0r8ykDZDSYHJ1s8XZQiJWSc55PLhDrMd2pVhMPrcpdDGki2hUby6EKunos1ED-7rztty2wdZFbY-FzfR287uyKqclcb6kOYN62PAZMvmJA5DDwqHLpl85ceBHdvmh610ZnEeOxmGwSmta7awqcXvdqR8UjQy7oZLwM2ifXrZBBK4Pc0BwQu4U0xsRHV-HWhRC_p2q9iNhnIg0J__5_7jFWmQGJqqf9KV2W7HBDSro31dZuRAgSCk5kONn2xEYL0AKawClgzzaox1UbPvtSLsYqLQZKqzD7XEqPzrrbQCT2rTOJzBLfTam943FCPL8IDpO3HBLSDz6-iSR-4IuicE32_lnM7yzL7akVPNn-2ue6houa9qUaltJEcYnMO-CQngldhyTrxsmFoiC4I-XSF2KsP8O3b00gxqAMeHHE4-p-eTILQRExsjMtw1DAACfZk7VlAbom2m01MFIgiuqaIBwbsbZdrlD29BWeNbAE8buAlQKlnooXMLzAu5jBmeELQPlDXohnIAb2zROcbUExvwo7sBCV8vw20gv3-uHRw24eREXsdRLYi-tTqlxRyMuYe1zOmajo_hHNNEXAMn9DYSrNOlgDBYWgfuIwTtpcEMrDDSqJSJ9q5EtfXygW5M0E_dq1emfgfMIH-ypHBj0ut2K0GOqVc1IvqYS4EINg4c-Ucys7-Armsl4FBNLj78U5i2XWDz2UFXYh9FmGXgLSoNFQd-C9bQECZdSsstnBUus68AF9W0Ze6CLQsuj7mBXsiJd2PokYHT3D6usJekv1dmmJWdOy2IkpKDA1rWEQMxpbwWn9yACm-EBTQew_0D2EuaTq5EiCrGigk4b4B8Z0EOhfvizlONG1ueoSh7xEoJG2wPNf9yPiv-MlebCgBFusg6aRYhKHY5qfDdMaAco3OXmVqSkOSgjqriTuO2vBzE5CiZraEv-dV7hqXk8sXy9u1OhySIbLMjJqQJSjk0KSNqHCK-1UedsP32lHx_rmUbstdXij3NMj0aF58315B1Bx2WcA327EZjzlsMlWY0GKySSiKLJW27IM1bYA
Goldberg, C. S., Lu, M., Sleeper, L. A., Mahle, W. T., Gaynor, J. W., Williams, I. A., ... & Newburger, J. W. (2014). Factors associated with neurodevelopment for children with single ventricle lesions. The Journal of pediatrics, 165(3), 490-496.https://www.sciencedirect.com/science/article/pii/S0022347614004466?casa_token=CcP091Pzk54AAAAA:TPCYgB0Usb8I33s-wGlelOxWtdmgH74ho7i_-41y99VXlJ33_SyYmkKXiayy3LFbiY3NhpgI
Marino, B. S., Lipkin, P. H., Newburger, J. W., Peacock, G., Gerdes, M., Gaynor, J. W., ... & Mahle, W. T. (2012). Neurodevelopmental outcomes in children with congenital heart disease: evaluation and management: a scientific statement from the American Heart Association. Circulation, 126(9), 1143-1172.https://www.ahajournals.org/doi/full/10.1161/CIR.0b013e318265ee8a
Mussatto, K. A., Hoffmann, R. G., Hoffman, G. M., Tweddell, J. S., Bear, L., Cao, Y., & Brosig, C. (2014). Risk and prevalence of developmental delay in young children with congenital heart disease. Pediatrics, 133(3), e570-e577.https://watermark.silverchair.com/peds_2013-2309.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAA6UwggOhBgkqhkiG9w0BBwagggOSMIIDjgIBADCCA4cGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQM7qLem9IQ0pI3ZDVZAgEQgIIDWP6NcYo1W2exXs_TVVgxIFpEL81-d9CrW73rdjSMw8R4aIwm-nvteifws2G1hxHT1J5VcKUSRBBl7ZemszxibmU_pkOx9ZToYOy11BLqlOh4882TffnPeXeMmScjgxjGEjJdVuI59OY6YaKi2kUusc6Hp_wo8jWAJ4qIQ5fW15GfUt3ZkGZsFHJ6b2YZmjlRIqUEiJjq6yEgRf9jaXjAyR8U6GUgI9X7S1YBl_aeiHwgOdS7jvCJVzwR_jq2qr7H3g4-QO_t8Xu9Psktjo9kLgx_gPQ83KQ6Xc81uBEXvT5rneMOnV2e62XWwVzDaLEfPXZ3yN8S0dqHDVMnEnVqdDCF2tChCM6n7MmBR6G7dpJVyfdBsa0xRPTOl1idw1hZXMQ9nmkD8hu49cTqTBHi5Xw1tnv3mBGskBVZTLRU-bToP-giz-P-aKup9YlQYyrr30p9rVcvxt9GjWQsaOIrTcZc6EzHbupIOiGOqWAna4WKuRwfKBc6pyI8xp8K7ADu7pL574dXmdULzPlo2Ku22Vo8k6ZYr-gMkK_KEkf1aVGr4HRQt-na11GQVD_a9zhgZjOLlLJjHeKDupon3GNWMyaUhlukNfm1oGMlgcgE5vZZsO5cKdf_SgZXrIQS_ypUnYqmT7twmSN2akfl6vmEJwsIWTEuoPoHBM2gFQul60lDzh0GT0gELTjMxvi9TCIMMxjsi3wnwM1W0GYf9bt_DdFm-HXwzypf2kBnc0yKu4YBnBKY5f7NoO8dnFc5qZxcmoHWXSVFDuXbGXDV6NmV3rmEwFV3T8f7unIdmyn5fgvZYrSeAEAS5CmTzj7fq6r0jNZIvOL7zswZB_QQSjXouPSgDaCdFFwOKjHVV6fW-u4zxJRl0kJi1IfuoSB6HvKxcDUlcyiBpWHYnmAYmwe0V7-gUOAHJ5parK17kOHf3_CdssD1oIjw2Y8otZBP1z_A0Czg_x0J5HL_daUyocw5LWU_FqO9bpB0QhfWfng3Weihm0U89h3_RAuLAiiQpIsv2DFQe8G3q8WrM1UMBKgbYmAEstxprXgS9NXAB9eLz88q5cibFQjL2kIiM1e9q76txogIZ8H3x3BF9q0fa3bfBffUdQuzQU47arunmXq2xShlW9PP0r1LgNw
Ryan, K. R., Jones, M. B., Allen, K. Y., Marino, B. S., Casey, F., Wernovsky, G., & Lisanti, A. J. (2019). Neurodevelopmental outcomes among children with congenital heart disease: at-risk populations and modifiable risk factors. World Journal for Pediatric and Congenital Heart Surgery, 10(6), 750-758.https://journals.sagepub.com/doi/pdf/10.1177/2150135119878702?casa_token=395nK7Zp3-sAAAAA:IUwUifZsx2ovYqctoavLP6Kyk3gnHFXaAR9e61_5gIiSCugFZdhmiScDMYKgPwY0UQAw8GfzegY
Sanz, J. H., Anixt, J., Bear, L., Basken, A., Beca, J., Marino, B. S., ... & Ilardi, D. (2021). Characterisation of neurodevelopmental and psychological outcomes in CHD: a research agenda and recommendations from the cardiac neurodevelopmental outcome collaborative. Cardiology in the Young, 31(6), 876-887.https://www.cambridge.org/core/services/aop-cambridge-core/content/view/065B89B2B7E17279B31473B0B546C947/S1047951121002146a.pdf/div-class-title-characterisation-of-neurodevelopmental-and-psychological-outcomes-in-chd-a-research-agenda-and-recommendations-from-the-cardiac-neurodevelopmental-outcome-collaborative-div.pdf
Sood, E., Newburger, J. W., Anixt, J. S., Cassidy, A. R., Jackson, J. L., Jonas, R. A., ... & American Heart Association Council on Lifelong Congenital Heart Disease and Heart Health in the Young and the Council on Cardiovascular and Stroke Nursing. (2024). Neurodevelopmental Outcomes for Individuals With Congenital Heart Disease: Updates in Neuroprotection, Risk-Stratification, Evaluation, and Management: A Scientific Statement From the American Heart Association. Circulation.https://www.sciencedirect.com/science/article/pii/S1098360022007213
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